Stata command for calculating adverse event and efficacy stopping boundaries for phase II single-arm trials
Abstract. Many programs and functions in statistical packages focus on the final
stage of clinical trials, that is, the data analysis. In this article, I aim to assist in the
early stages of clinical trials, specifically, the design of phase II single-arm trials.
I present the new command stopbound, which calculates stopping boundaries and
operating characteristics based on monitoring an adverse event, efficacy, or an
adverse event and efficacy.
View all articles by this author:
Bryan M. Fellman
View all articles with these keywords:
stopbound, Bayesian clinical trial design, adverse event, efficacy rate, futility, simulation, operating characteristic
Download citation: BibTeX RIS
Download citation and abstract: BibTeX RIS
|